Investigation of application of ALT / ALP ratio in the differen- tial diagnosis of jaundice

Objective: To study the value of ALT / ALP ratio (R value) for the differential diagnosis of hepatocellular jaundice and cholestatic jaundice and compare the diagnostic sensitivity of R values and the traditional D / T (DBIL / TBIL) values. Method: We randomly collected 336 cases patients with confirmed diagnosis of dominant jaundice from January 2004 to December 2006 in our hospital and recorded their ALT, ALP, TBIL and DBIL information to calculate the R value and D / T values. Results: The R value for the positive rate of diagnosis of hepatocellular jaundice is 34.9%, and D / T value is 16.1%, with R> D / T (P <0.05). For cholestatic jaundice, the D / T value for positive diagnostic rate is 93.0%, and the R value is 75.4%, with D / T> R (P <0.05). Conclusion: For the positive rate of diagnosis of hepatocellular jaundice, the R value is higher than D / T, while D / T is better than the R value for the positive rate of diagnosis of cholestatic jaundice.